New Treatment Methods in Hair Loss in Men and Women

New Treatment Methods in Hair Loss for full hair in the future.

There are several forms of hair loss in men and women and new treatment methods. You may ask: What’s New For Hair Loss Treatment?

New Treatment Methods in Hair Loss research from Mrs. Angela Christiano. She is a researcher at Columbia University. She has a condition known as alopecia areata. It leads to sudden and significant hair loss. Because she is not satisfied with the treatments on the current market, she and her team go a new, different way. Currently, there are only two approved hair loss drugs on the market and both are more than 20 years old.

Propecia, Rogaine, and Minoxidil

The best hair loss drugs on the market are Propecia and Rogaine. Minoxidil is the only approved treatment for women. Therefore it is important to develop a new treatment for women’s hair loss. Propecia alters hormone levels so much that pregnant women are advised not to even touch the pills, as their new approach is shown in this article. She transforms the patient’s own stem cells, which theoretically can transform into any type of cell in the body into the hair.

Alopecia Areata

Many see the hair loss problem as a cosmetic problem, traditionally. It attracts less attention than the major medical challenges of cancer or AIDS. The most immediate and worst disease is alopecia areata. Here the immune system attacks the hair follicles. The hairs are regarded as enemies of the body and are repelled. Another is androgenic alopecia, which causes the hair to fall out in tufts. This is a genetic form of hair loss. It affects both sexes and could begin in very early years. We had a student at the Fachhochschule Braunschweig who was already bald at the age of 24.

New Treatment Methods in Hair Loss picture of bold man

Another form is the usual hair loss due to aging, which also occurs in both sexes. Half of all women have some form of a specific form of postmenopausal hair loss. E.g. Americans spend about $3.5 billion a year on hair loss products. Most of them have no effect at all.

New Treatment Methods in Hair Loss is the WNT Pathway

Samumed, a San Diego-based start-up company, is working on hair loss and diseases such as osteoarthritis and pancreatic cancer. The company’s approach focuses on a molecular signaling channel, the WNT pathway, which plays an important role in hair growth. This approach does not destroy hormones. Two Phase 2 studies have been conducted in the treatment of male hair loss. In one study with over 300 patients, participants were given a low dose of the drug. The number of hairs in these patients increased by almost 10 percent over a period of 135 days.

The placebo group continued to lose hair. The study was not published or reviewed. Samumed presented the results last spring at a meeting of the American Academy of Dermatology. So far the drug has only been tested in men because androgenetic alopecia is a major disease in men. Growing rat hair “as if there was no tomorrow”.

JAK Inhibitors

Christiano follows a different approach – or actually two different approaches. She is developing a hair loss drug from so-called JAK inhibitors. This is supposed to dampen the activity of a class of enzymes called Janus kinase. Two JAK inhibitors have been approved by the FDA for rheumatoid arthritis, psoriasis and one type of skin cancer called myelofibrosis.

In one study, an affected person handled with compounded ruxolitinib 0.6% cream implemented twice each day for 12 weeks to the eyebrows and scalp led to finish eyebrow regrowth and partial scalp hair regrowth30. Scientific trials with topical ruxolitinib and topical tofacitinib are presently underway in aa

These two are also used for other autoimmune diseases, including hair loss, and another problem is to be solved for hair transplant surgery. Hair is usually removed from the back of the head and implanted on top of the head. But there is only a limited amount of hair that can be removed from your body. The challenge is to transform the stem cells of the scalp into real hair follicles. So far, it has only been scientifically possible to transform them into standard fibroblasts. These are the cells that form generic connective tissue.

PRP is a New Treatment Methods in Hair Loss

In the laboratory of Christiano, hair now grows on a 3-D scaffold made of tissue culture. A mixture of growth factors has been poured over it. Actually, hair grew on it after a while. “Rat hair, that is, we can grow rat hair as if it were not tomorrow,” Christiano said.

Another new technique is called PRP (platelet-rich-plasma). PRP is designed to stimulate the growth of lazy hair follicles. This method is very suitable for women, it takes a patient’s blood, turns it in a centrifuge to extract the plasma, isolates growth factors from the blood follicles, adds nutrients and then injects the mixture back into the patient scalp.

Guidance and injection of PRP

To put together PRP, the blood of a patient is spun in a centrifuge to split the platelets from different blood components and bring a platelet-rich-plasma that may be collected and treated. As soon as the injection has been given, the affected person must keep away from exercising or weight-bearing interest for 3 to 7 days, earlier than progressively returning to their traditional physical sports. For the period straight away following injection, a health practitioner may additionally advise the use of a cast, boot, or brace.

 

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